Dienogest

17α -hydroxy-3 -oxo- 19β - norpregna -4 ,9-diene -21 -nitrile

  • G03AA17
  • G03FA15

Progestins

209-214 ° C

4000 mg · kg -1 ( LD50, mouse, oral)

Template: Infobox chemical / molecular formula search available

Dienogest is a synthetic progestin, which is used as hormonal contraceptive for birth control and for treatment of problems, acne and endometriosis in women.

Dienogest has an anti-androgenic effect and thus belongs to the receptor blockers. Dienogest has the only 19 -Norge days no estrogenic, anti-estrogenic or androgenic partial action.

History

Dienogest was first synthesized in 1979 as STS 557 in Jena. It showed the 10-fold potency compared to levonorgestrel. In 1995, the micro pill Valette ® from Jena Pharm was put on the market.

Trade names

Visanne 2 mg (D, CH)

Aristelle (D), Climodien (D), Lafamme (D), Motion ( A), Qlaira (D, A, CH), Valette (D, A), Maxim (D), Velafee (D)

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Progestogen Antiandrogen Selective estrogen-receptor modulator Jenapharm Digital Object Identifier
290034
de