Diphenylpyraline

  • 4- benzhydryloxy - 1-methylpiperidine
  • 4 - ( diphenylmethoxy )-1- methylpiperidine (IUPAC)

R06AA07, R06AA57

  • First generation antihistamine
  • Antiallergic

30 ° C.

158-160 ° C (266 Pa)

Hydrochloride

Attention

Hydrochloride

Template: Infobox chemical / molecular formula search available

Diphenylpyraline is a drug which is used as a systemic anti-allergic use.

It belongs to the drug class of first-generation antihistamines or to the group of aminoalkyl ethers.

Diphenylpyraline was in Germany (as an anti-influenza drug ) and Switzerland (as peroral cold remedy ) in the form of combination products on the market.

In addition to the anti-allergic effect the drug is attributed to a antisecretory effect.

Chemical Synthesis

The compound can be prepared by alkylation of 4-hydroxy- 1-methylpiperidine with benzhydryl bromide:

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System DrugBank Dangerous Substances Directive (67/548/EEC) Active ingredient Chemical classification Diphenylmethane Digital Object Identifier
290441
de