DNA sequencer

(DNA) sequencing machines, and DNA sequencers, DNA sequencing and DNA sequencers, are laboratory instruments for automatic evaluation of DNA sequencing. Sequencing machines take over either the separation and analysis of the resulting Sanger dideoxy method with the fragments or the full implementation of next generation sequencing methods.

History

The first automated sequencing was developed in 1986 by Leroy Hood and colleagues at the California Institute of Technology (Caltech ) and was based on the common electrophoretic separation of four Sanger Sequenzieransätzen, which were carried out with fluorescently labeled primers in a Polyacrylamidsäule.