Galanin

  • OMIM: 137035
  • MGI: 95637

Galanin is a neuropeptide that is present in the central nervous system and peripheral nervous system. The galanin in humans consists of 30 amino acids. In the central nervous system is involved galanin in the regulation of release of various neurotransmitters. Its regulatory effect on acetylcholine release is associated with its participation in the pathogenesis of Alzheimer 's disease.

Galanin may also at various other neurological effects, such as the inhibition of epileptic seizures and pain involved.

In the peripheral nervous system of this neuropeptide influenced the motility of the gastrointestinal tract.

In addition, galanin can act on the endocrine system by controlling the release of prolactin, LH and somatotropin. These effects of galanin are three different G-protein - coupled receptors mediates: GALR1 - GALR3.

  • Neuropeptide
  • Digestive physiology
Human Genome Organisation Mouse Genome Informatics Euteleostomi Entrez Ensembl UniProt National Center for Biotechnology Information
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