GRIA 3

  • OMIM: 305915
  • UniProt: P42263
  • MGI: 95810

The Glutamate receptor, ionotrophic, AMPA 3, also known as GRIA3, is a human protein.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the brain of mammals. They are heteromeric protein complexes that are composed of different subunits. Each subunit has a transmembrane domain. Together, they form a ligand-gated ion channel. The glutamate receptors of the type GRIA 1-4 ( also GluR1 -4) are due to its activation by the agonists alpha- amino-3- hydroxy-5- methyl-4- isoxazole propionate to the so-called AMPA receptors. GRIA 3 is also expressed on lymphocytes, and was treated as a candidate gene for various disorders, including Rett syndrome, encephalitis, Rasmussen, bipolar disorder, and X -linked mental redardation syndrome Smith- Fineman -Myers.

Protein isoform Human Genome Organisation Mouse Genome Informatics Entrez Ensembl National Center for Biotechnology Information Science (journal) Biochimica et Biophysica Acta
279710
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