Hexobarbital

• (RS ) -5 - (1- cyclohexenyl ) -1,5 - dimethylbarbituric acid IUPAC
• (±) -5 - (1- cyclohexenyl ) -1,5 - dimethylbarbituric
• Latin: Hexobarbitalum
• Evipan

• N05CA16
• N01AF02

White and very hygroscopic powder with a bitter taste

Barbiturates

146.5 ° C

8.2 (20 ° C)

Water: 435 mg · l-1 (25 ° C)

Attention

270 mg · kg -1 ( LD50, mouse, ip)

Template: Infobox chemical / molecular formula search available

Hexobarbital is one belonging to the group of barbiturates Injektionsnarkotikum or short-acting sleeping pills with addictive potential, which is rarely used today and is a racemate.

Pharmacological effects

Most barbiturates act as sleep aids; Hexobarbital here shows an extremely short duration of action. All hypnotic barbituric acid derivatives lead to physical dependence, very similar to the effects of alcohol. Typical withdrawal symptoms of hexobarbital addicts include irritability, nervousness, hand tremors, disturbances of muscle coordination, decay of the reaction and ability to articulate and even delirium tremens.

Chemical Properties

Hexobarbital is a methylated Oxybarbiturat ( barbiturates ), and a weak acid having a melting point of 145-147 ° C. As many derivatives of barbituric acid, it can be used as buffering agent in an aqueous solution due to its acidic and basic properties.

It is used often in the form of its sodium salt ( Privenal, CAS: 50-09-9 ), which is more soluble in water.