Isopentenyl-diphosphate delta isomerase

Isopentenyl diphosphate isomerase ( IPPI ) are called enzymes that catalyze the rearrangement of isopentenyl diphosphate (IPP ) to dimethylallyl diphosphate (DMAPP ) and vice versa. They occur in all living things. There are two non-homologous types of IPPI, Type I occurs only in eukaryotes and some bacteria, while the FMN -dependent type can be found in bacteria and archaea. For animals, the reaction step is important for the biosynthesis of cholesterol. In man, there are two isoforms, the second of which occurs only in the muscles.

Catalyzed reaction

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Isopentenyl diphosphate (IPP ) and dimethylallyl diphosphate (DMAPP ) merge.

Protein isoform Isopentenyl pyrophosphate Digital Object Identifier PubMed Central
416441
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