John Jacob Abel
John Jacob Abel ( born May 19, 1857 in Cleveland, Ohio, † May 26, 1938 in Baltimore, Maryland) was an American biochemist and pharmacologist.
Life and work
Abel in 1876 to study at the University of Michigan in Ann Arbor, which he however had to 1879-1882 break for financial reasons. He studied medicine, pharmacology, biochemistry and chemistry at the Johns Hopkins University in Baltimore and at Carl Ludwig at the University of Leipzig. He also studied in Strasbourg, Wurzburg, Heidelberg, Vienna, Berlin and Paris. In Strasbourg he received his doctorate in 1888 for Dr. med. In 1891, he was Professor of Medicine and Therapeutics at the University of Michigan in Ann Arbor and in 1893 he was appointed Professor of Pharmacology at the Johns Hopkins University and remained there until his retirement in 1932.
Abel is considered one of the pioneers of early hormone research and was known for his investigations of the adrenal hormones adrenaline. Thus he was able in 1897 as the first isolate the adrenaline beside Napoleon Cybulski and Jokichi Takamine; he called it " epinephrine ". In 1926 he presented the hormone insulin crystalline dar. His search for the central pituitary, however, remained unsuccessful, it turned out later that this is a variety of hormones.
John Jacob Abel is co-founder of scientific journals Journal of Biological Chemistry (1905 ) and Journal of Pharmacology and Experimental Therapeutics ( 1909). In 1925 he was elected a member of the Scholars Academy Leopoldina.
The name of its founder gives honoring the American Society for Pharmacology and Experimental Therapeutics annually the " John J. Abel Award in Pharmacology and Experimental Therapeutics " for original and outstanding research achievements of a pharmacologist under 42 years.
Significant writings
- About the blood pressure -causing part of the adrenal gland, the epinephrine. In: Journal of Physiological Chemistry, 28, 1899, pp. 318-362.
- Some recent advances in our knowledge of the ductless gland. In: Bulletin of the Johns Hopkins Hospital, 38, 1926; Pp. 1-32.