Kochi reaction

The Kochi reaction is used to represent secondary and tertiary hydrocarbon chlorides ( halocarbons ) of monocarboxylic acids. Therefore, it is also referred to as rare Halodecarboxylierung. In the presence of lead tetraacetate as oxidizing agent, and calcium chloride or lithium chloride in refluxing benzene, the reaction is carried out. The carboxylic acid is oxidatively decarboxylated and converted with present lithium chloride to the end product. Through the elimination of CO 2 ( decarboxylation), the molecule shortened by one carbon atom.

Another variant is the Hunsdiecker reaction, in which extend a few reaction steps according to a radical mechanism. Both reactions have a great importance in the synthesis chemistry, on the one hand carboxylic acids on the other hand, the halogen compounds are very easily accessible and much more reactive than the carboxylic acids.