Möbius syndrome

When Möbius syndrome ( synonym: okulofaziale palsy) is a rare, congenital syndrome, which occurs sporadically and manifests itself primarily through a bilateral paralysis of the mimetic facial muscles ( Bell's palsy ). The cause is suspected in a Kernaplasie in the brainstem. The movements are limited to the extent that, for example, smile or frown can be difficult or even impossible and the face gets a mask-like expression. Combinations with disorders of eye muscles, especially a sixth nerve palsy, and paralysis due to lesions below ( infranukleär ) or above ( supranukleär ) of the nerve nuclei, for example, view paralysis, are common.

In some cases, the Möbius syndrome with other physical impairments is as deformities of fingers and hands, hand in hand. Another, albeit rare, connection is associated with ear malformations, hearing loss and deafness. Combinations with other syndromes, such as the Kallmann or Poland syndrome, are possible.

A life without facial expressions and in particular mimic laughter encounters in the social environment repeatedly to rejection and is associated with specific exclusion. Each socialization phase arises as a great challenge The disease was first in 1888 by the German neurologist Paul Julius Möbius ( 1853-1907 ) described.