N-Acetylneuraminic acid

  • NANA
  • NeuNAc
  • Neu5Ac
  • Sialic acid ( collective term for several substances )

White solid

Fixed

184-186 ° C ( decomposition)

Moderately in water (50 g · l-1 at 20 ° C)

Attention

Template: Infobox chemical / molecular formula search available

N- acetylneuraminic acid ( NANA of abbreviated English: N- Acetylneuraminic acid), the most common sialic acid, is a component of the glycocalyx. It binds calcium to macromolecules and cells. Since calcium is an important inter-and intracellular messenger, NANA thus forms a messenger carrier.

In the human N-acetylneuraminic acid occurs only what it. Of other mammals, including primates, in addition to the acetylated form also a glycolated, which is N - glycolylneuraminic acid having, different

Production and representation

NANA goes through two reactions from mannosamine out:

  • Addition of a Pyruvatrests to the C1 atom (Product: neuraminic )
  • Acetylation of the amino group
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