Nucleocytoplasmic large DNA viruses

The term Nucleocytoplasmic large DNA viruses ( NCLDV ) refers to a group of large eukaryotic viruses of the families Asfarviridae, Iridoviridae, Marseilleviridae, Megaviridae, Mimiviridae, Phycodnaviridae, Poxviridae and Pandoraviridae. A no virus family assigned provisional genus Dinodnavirus is also part of this group. The term is a non- taxonomic collective term relationship without remuneration.

Reasons for creating the NCLDV Group

All members of this group have common and unique features of the genomic DNA and the virion structure. It remains unclear whether the similarities between the members of the group result from that they have inherited from a common host during replication similar genes or whether they have a common ancestor. The last alternative is considered to be controversial. So far, 47 are known NCLDV core genes. They include four genes that affect DNA replication and repair mechanisms: the DNA polymerase family B, topoisomerase II A, the "flap " endonuclease and the ring clamp protein proliferating -cell nuclear antigen, and RNA polymerase II and the transcription factor IIB