Oxypurinol

Colorless acicular crystals

Fixed

> 320 ° C

Risk

Template: Infobox chemical / molecular formula search available

Oxypurinol is a chemical compound from the group of pyrazoles. The substance acts in the metabolism by inhibiting the formation of uric acid. Too high uric acid levels can contribute to the formation of kidney and bladder stones and gout cause.

Oxypurinol, the active metabolite of the drug allopurinol, but is not itself used as a drug.

Mechanism of action

Oxypurinol irreversibly inhibits (suicide inhibitor), the enzyme xanthine oxidase, xanthine, an intermediate in the Purinabbau oxidized to uric acid. Thus, xanthine and hypoxanthine are excreted in the urine increases, causing the uric acid levels in the blood and urine falls.

Oxypurinol is excreted unchanged by the kidneys.