P-Anisic acid

  • 4 -methoxybenzoic acid
  • P-methoxybenzoic

Colorless crystalline needles

Fixed

1.39 g · cm -3

183 ° C

277 ° C.

4.47

  • Very poor in water (about 0.3 g · l-1 at 20 ° C)
  • Insoluble in ethanol, chloroform and diethyl ether

1.571 to 1.576

> 5000 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Anisic acid is methoxylated benzoic acid, methoxybenzoic acid and thus one that is both a carboxylic acid and an ether.

Occurrence

Anisic acid is found in small amounts (eg, vanilla) before the oil of anise and other plants.

Production and representation

Anisic acid can be obtained by reaction of 4- methoxyacetophenone with hypobromite ( Einhorn reaction ).

Another very simple synthesis of anisic acid, the oxidation of anisaldehyde with an oxidizing agent such as potassium permanganate.

Use

Anisic acid used for the preparation of anisic acid derivatives. It is bacteriostatic and was formerly used as an antiseptic, anti-inflammatory drug and a preservative.

Safety

The vapors of anisic acid can form (185 ° C, ignition temperature 280 ° C flash point) with air to form an explosive mixture.

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