Panton-Valentine leukocidin

  • UniProt: P31716

Leukocidin ( luk ) (composed of the short form of leukocyte ancient Greek λευκός leukos "white" and an ancient Greek κύτος CYTOS " cavity ", " envelope ", " vessel " and Latin caedere " cut down ", " kill " ) is the name for several pore-forming toxins, which are formed by the bacterium Staphylococcus aureus, whose phage PVL, and the phage φCTX of Pseudomonas aeruginosa. Leukocidin in particular says below the bacterial protein from Staphylococcus.

Leukocidin (deprecated γ -hemolysin ) consists of two subunits ( Luk-F/Luk-S ). It destroys granulocytes and macrophages. The bacterium prevented to be phagocytosed and eliminated. It is one of the virulence factors ( disease-causing properties) of Staphylococcus aureus strains.

Medical Subject Headings
194623
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