Prochlorperazine

2-chloro- 10 -[3 - (4-methyl -1-piperazinyl ) propyl] -10H -phenothiazine

• 58-38-8
• 84-02-6 ( hydrogen maleate )

N05AB04

Template: Infobox chemical / molecular formula search available

Prochlorperazine is a dopamine receptor antagonist is selected from the group of phenothiazines, which is mainly for nausea and vomiting ( as an antiemetic ) and in migraine, rarely used as an antipsychotic.

Indications

Prochlorperazine is used as an antiemetic to treat nausea and vomiting, as antipsychotic used to treat schizophrenia and anxiety disorders as well as for migraine treatment.

Side effects and interactions

As typical unwanted effects of prochlorperazine are " blurred vision, chills, constipation, dizziness, drowsiness, dry mouth, nervousness, stuffy nose, insomnia, severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue); Agitation altered mental abilities that do not move immediately to your environment, changes in the breast, changes in the period, blurred vision, difficulty swallowing, drooling, excessive sweating, fever, inability to eyes, increased body temperature, involuntary movements of the tongue, face, mouth or jaw (eg, protrusion of tongue, and then blew the cheeks, puckering of mouth, chewing movements ), irregular or rapid heartbeat, mask like face, muscle stiffness, muscle spasms of face, neck or back, prolonged or painful erection; restlessness; stiff muscles; Go mixing; Sore throat; Tension in the legs; Tremors, twitching or turning movements, unusual eye movements, weakness of the arms or legs, yellowing of the skin or eyes " (quoted from ) known.

The drug may for example not be used concurrently with astemizole, cisapride and terfenadine.

Trade names

Monopreparations: Compazine (USA)