Pyoverdine

The Pyoverdine are a group of currently 60 known fluorescent siderophores and oligopeptide antibiotics that are produced by the Gram-negative bacteria Pseudomonas aeruginosa and Pseudomonas fluorescens.

Pyoverdine serve in pseudomonads induction of virulence factors. Pyoverdine be divided into three types, each Pseudomonadenstamm produces only one type. In Pseudomonas aeruginosa PAO1 14 PVD genes are involved in the synthesis of Pyoveridine.

Unlike Enterobactinen Pyoverdine are iron-binding, non- ribosome peptide containing a dihydroxyquinoline derivative. The structure of the peptides is different between different Pseudomaonaden, and more than 40 structures have been described. The actual chromophore (1S )-5 -amino-2 ,3-dihydro -8 ,9 -dihydroxy -1H- pyrimido [1,2-a ] quinoline -1 -carboxylic acid, however, is the same, with the exception of Azobaktin of Azotobacter vinelandii, which contains a further ring urea.