Quinazoline

• Phenmiazin
• 1.3 Benzodiazin
• 1.3 Diazanaphthalin
• 4.5 - benzopyrimidine
• Benzo [e ] pyrimidine

Light yellow solid

Fixed

45-48 ° C

243 ° C.

Template: Infobox chemical / molecular formula search available

Quinazoline is a condensed heterocyclic aromatic organic compound having 2 nitrogen atoms, consisting of a benzene or a pyrimidine ring.

Derived molecules

• Chinazolinalkaloide are alkaloids with quinazoline as a core fragment, eg vasicine ( peganine ) and febrifugine. Their biogenesis is as for the Acridonalkaloiden via anthranilic acid. Chinazolinalkaloide come in Acanthaceae ( Adhatoda vasica ), Rutaceae, Saxifragaceen ( Dichroa febrifuga ) and Linaria species (Fam. Scrophulariaceae ) Peganum harmala and ( Fam Zygophyllaceae ); also in animals (cf. tetrodotoxin ) and bacteria.
• Synthetic alpha blockers such as prazosin
• Sleeping like methaqualone
• EGFR tyrosine kinase inhibitors such as gefitinib, erlotinib, lapatinib, AEE788, EKB -569 and HKI -272