Seiji Ogawa
Seiji Ogawa (Japanese小川 诚 二, Seiji Ogawa, born January 19, 1934) is a Japanese biophysicist. He is one of the pioneers of functional magnetic resonance imaging (fMRI ).
Life
Ogawa acquired in 1957 at the University of Tokyo in Tokyo, Japan, a bachelor's degree in applied physics. From 1962 to 1964 he worked as a research assistant at the Laboratory of Radiation Research at the Mellon Institute in Pittsburgh, Pennsylvania. 1967 acquired Ogawa at Stanford University in Stanford, California, a Ph.D. in chemistry and remained there as a postdoctoral fellow. 1968 moved Ogawa at the Bell Laboratories in Murray Hill, New Jersey, where he rendered his most important research. In 2001 he went as a director of the Laboratory for Brain Function Research at the Hamano Life Science Research Foundation in Tokyo.
Work
Ogawa laid the foundations for a non-invasive, radiation-free pictorial representation of physiological and functional processes, especially of the brain, as he discovered in search of physiological signal changes in magnetic resonance imaging of the BOLD contrast, in which deoxygenated hemoglobin can be used as a contrast agent. The resulting method of functional magnetic resonance imaging ( fMRI ) and the suszeptibilitätsgewichteten imaging are the basis of many research and clinical applications in biology, neurobiology, psychology and neurology.
Other merits are in the Ogawa kernspinresonanzspektroskopischen in vivo studies of the relationship between structure and function of proteins, the cell metabolism and enzyme kinetics.