Sequence assembly

As an assembler, a computer program is called the virtual nucleotide sequences in bioinformatics, brought together by sequence alignments to longer fragments. In this case, an assessment, by a shotgun sequencing number of short DNA sequences ( reads eng. ) is arranged such that they form the original genome.

Software

AMOS (A Modular, Open - Source assembler ) is an open source project, which has set itself the goal of creating a modular and open-source assembler. The project was developed at the Institute for Genomic Research by Steven Salzberg, Mihai Pop and Art Delcher.

The Celera Assembler was developed by Gene Myers, Granger Sutton and Art Delcher at Celera 1998-2002. Since then, the project is being developed on SourceForge.

The Arachne assembler was launched in 2000 by Serafim Batzoglou as part of his doctoral thesis. Since then, he is a team led by David B. Jaffe, developed at the Broad Institute.

A list of available assembler can be found here: Available assembler (English ).