SLC23A1

The sodium-dependent vitamin C transporters in the cell wall of vertebrate cells contained proteins that catalyze the introduction of sodium ions and vitamin C in the cell. So it is to transport proteins. In humans, there are two of these transporters, named SVCT1 and SVCT2, which are encoded by the genes SLC23A1 and SLC23A2. SVCT1 is particularly in the small intestine, kidney, ovary, colon and liver, before, during SVCT2 has no specific localization.

The transport equation is:

It is a symport.

Variants of SVCT2 may be associated with the occurrence of colorectal cancer. SVCT2 seems out of sodium or of calcium, or magnesium to be dependent. This is still the topic of current research.

Protein isoform Human Genome Organisation Euteleostomi Transportprotein Large intestine Digital Object Identifier
595018
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