Spermatogonium

Spermatogonia (singular spermatogonial or spermatogonia ), also immature germinal cells, the stem cell population in the germinal epithelium of the testes. This to sperm fixed to a tissue-specific stem cells arise from primordial germ cells develop according to their migration into the testis investment in the course of the first mitotic cell division in spermatogenesis. They are found in the basal portion of the seminiferous epithelium directly to the basement membrane and have a rounded nucleus chromatin. In contrast to the egg cells that no longer proliferate, can multiply spermatogonia and so always make new initial populations for spermatogenesis.

Research

Scientists have succeeded, to rejuvenate spermatogonia from the testes of adult men under the influence of a growth factor and an inhibitor to pluripotent cells, which therefore can transform into any cell type of the body itself. Through experiments, it was demonstrated that these reprogrammed in such germ-line stem cells meet all the molecular and functional requirements, which are also placed on human embryonic stem cells ( ES cells).