Stephen C. Harrison
Stephen Coplan Harrison ( * in New Haven, Connecticut) is an American biochemist and professor at Harvard University, Cambridge, Massachusetts.
Life
Harrison purchased in 1963 from Harvard College Harvard University a bachelor's degree in chemistry and physics, and in 1967 at Harvard University even a Ph.D. in biophysics. As a postdoctoral fellow he worked with Aaron Klug at the University of Cambridge in Cambridge, England, at Lowell House at Harvard University and the Children's Cancer Research Foundation (now the Dana -Farber Cancer Institute ) in Boston, Massachusetts.
After working at the University of Cambridge and the Children's Cancer Research Foundation Harrison received a PhD Student ( Assistant Professor in 1971, Associate Professor 1975) of Biochemistry at Harvard University. Research and teaching assignments have taken him 1971/72 to Heidelberg ( Max - Planck - Institute for Medical Research and Ruprecht -Karls -Universität Heidelberg ) and 1977 to Cambridge ( Trinity College and Medical Research Council ).
Since 1977, Harrison heard as a full professor at Harvard University, first as Professor of Biochemistry and Molecular Biology at Harvard University, since 1996 also professor of Biochemistry and Molecular Pharmacology and of Pediatrics at Harvard Medical School. In 1996 he was also the Head of the Laboratory for Molecular Medicine at Children's Hospital of Boston. Since 1987, Harrison conducts research in addition to the Howard Hughes Medical Institute ( HHMI ) in Boston.
Other academic positions for various institutions Harvard University and Harvard Medical School followed, often in leading position.
Work
Harrison using X-ray crystallography ( crystal structure ), to investigate viral DNA -protein complexes and membrane receptors. Here he was able to achieve significant improvements and innovations in the methods. The combination of structural analysis and cell biological methods led to a deeper understanding of the structure of viruses of the interactions between DNA and proteins and cellular signals.
Current research projects are concerned with the mechanisms of viral replication, with clathrin- occupied vesicles and the structure and function of kinetochores.