Triton X-100

  • Octoxynol 9
  • ( p-tert- octylphenoxy ) polyethoxyethanol
  • O-[ 4 - ( 1,1,3,3- tetramethylbutyl ) phenoxy] polyethoxyethanol
  • Polyethylene glycol [4 - ( 1,1,3,3- tetramethylbutyl ) phenyl] ether

Colorless to yellowish liquid

Liquid

1.07 g · cm -3

6 ° C

> 200 ° C

<1 Pa ( 20 ° C)

Soluble in water

Risk

1900 mg · kg -1 ( LD50, rat, oral)

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Octoxinol 9 ( INN) is a p-tert- octyl phenol derivative with a polyethylene glycol side chain with 9 to 10 ethylene oxide units. It is a nonionic surfactant from the group of octylphenol ethoxylates. A well-known product of this series is Triton ® X-100.

Properties

Octoxinol 9 can change the melting behavior of DNA double strands.

Use

Octoxinol 9 is used as a detergent use in biochemistry. Since it does not denature proteins, it is used to extract the membrane proteins in their native conformation, in contrast to membranes made ​​of SDS. It is also used for virus inactivation by the solvent detergent method.

Octoxinol 9 is used as a substitute substance for the spermicide nonoxynol 9 and as a pharmaceutical excipient.

CAS registry number Vapor pressure Dangerous Substances Directive (67/548/EEC) Biochimica et Biophysica Acta Digital Object Identifier
607264
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