Riboflavin kinase

Flavokinase ( riboflavin kinase) is the enzyme in the metabolism of vitamin B2, riboflavin, which converts in the flavin mononucleotide ( FMN) and therefore essential for the synthesis of coenzyme flavin adenine dinucleotide (FAD) is. Flavokinase is produced by all living organisms, the enzyme of archaea is but from that of bacteria and eukaryotes very different. In humans flavokinase in the cytoplasm of the cells of the brain, placenta, and urinary bladder is located.

Catalyzed reaction

XTP → XDP

The catalyzed reaction is a phosphorylation at a phosphoric acid residue is transferred from a nucleotide triphosphate to the 5'-hydroxy group of the riboflavin.

For bacterial and eukaryotic Riboflavinkinasen (ATP - riboflavin -5'- phosphotransferases, EC 2.7.1.26 ) -catalyzed reaction is ATP - specific:

In archaeal Riboflavinkinasen ( CTP riboflavin 5' - phosphotransferases, EC 2.7.1.161 ) it runs CTP - specific:

Human Genome Organisation Mouse Genome Informatics Cofactor (biochemistry) Adenosine triphosphate Adenosine diphosphate Cytidine triphosphate Cytidine diphosphate
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