Carvacrol

• 5 -isopropyl-2 -methylphenol
• Isothymol
• Karvakrol
• Isopropyl -o-cresol
• Isopropyl -o-cresol
• 2-p- cymene

Smelling of thyme liquid

Liquid

0.9772 g · cm -3 ( 20 ° C)

~ 0 ° C

237-238 ° C

Insoluble in water, slightly soluble in ethanol and diethyl ether

1.5230 (20 ° C)

Risk

• 810 mg · kg -1 ( LD50, rat, oral)
• 73.3 mg · kg -1 ( LD50, mouse, ip)
• 80 mg · kg -1 ( LD50, mouse, i.v.)

Template: Infobox chemical / molecular formula search available

The carvacrol is a terpenoid natural substance which is known under different names. The systematic name (IUPAC ) of carvacrol is 2-methyl- 5-( 1-methylethyl) -phenol. The contribution to the thymol contains additional information.

Occurrence

Carvacrol comes under other in thyme (Thymus ), winter savory ( Satureja montana), summer savory ( Satureja hortensis ), oregano (Origanum ), Real Catnip ( Nepeta cataria ) and goose feet (eg Chenopodium ambrosioides ) ago. Oils derived from these plant species, which may contain up to 85% carvacrol. A plant with a particularly high carvacrol content is the Cretan mountain tea Malotira ( Sideritis syriaca ).

Features and Construction

The carvacrol is a higher homologue of o- cresol. Regulations on the Carvacrols go out in general on the safety of thymol.

Carvacrol is iron (III ) chloride, an olive green color.

Biological Significance

Carvacrol finds versatile use, mainly as a biocide. For it to be effective as an antifungal agent, insecticide, antibiotic and as an anthelmintic. Carvacrol also inhibits the inflammation -promoting enzyme cyclooxygenase -2 and equivalent in effect, therefore, the anti-inflammatory drugs, celecoxib and etoricoxib, inter alia, be used against rheumatism and gout.