Dennis Slamon

Dennis Joseph Slamon ( born August 6 1948 in New Castle, Pennsylvania) is an American oncologist and professor at the University of California, Los Angeles in Los Angeles, California.

Life

Slamon acquired in 1970 at Washington & Jefferson College in Washington, Pennsylvania, a bachelor's degree in biology in 1975 from the University of Chicago, Chicago, Illinois, both an MD as well as Winston Anderson and Werner Kirsten a Ph.D. in cell biology. From 1975 to 1978 Slamon worked as an assistant doctor at the University of Chicago Hospitals and Clinics from 1978 to 1979 as a senior physician ( Chief Resident ). 1978 erwarber the specialist in internal medicine ( internist ), 1982. Than consultant oncologist Since 1979, Slamon works in Hematology / Oncology at the University of California, Los Angeles School of Medicine, first as a Fellow, then as a professor (1982 Adjunct Assistant Professor, Assistant Professor in 1984, Associate Professor in 1988, Associate Professor in 1993 ).

Since 2013 it is one of Thomson Reuters due to the number of its citations to favorites to a Nobel Prize (Thomson Reuters Citation Laureates ).

Slamon is married.

Work

Slamons important work covers the HER2/neu-Rezeptor, an epidermal growth factor receptor, which is found strongly on the tumor cells of about 20 % of patients with breast cancer and directed against HER2/neu monoclonal antibody trastuzumab (trade name Herceptin), the growth of these cells inhibits. Slamons work is a particularly important example of the rapid clinical application of the results of basic research. Herceptin marked a paradigm shift in cancer therapy, as a chemotherapeutic agent could be developed targeted against specific properties of certain subgroups of tumors for the first time.

Slamons life and his efforts to explore the HER2/neu-Rezeptors and to the possibility of treatment with Herceptin have been filmed in the TV movie Living proof with Harry Connick Jr. in the lead role in 2008.

Awards (selection)

  • 2002 Gabbay Award
  • 2004 Medal of Honour for Clinical Research, the American Cancer Society
  • 2006 David A. Karnofsky Memorial Award from the American Society of Clinical Oncology
  • 2007 Gairdner Foundation International Award
Washington (Pennsylvania) Specialty (medicine)
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