Lowest published toxic dose

The smallest known toxic dose (English toxic dose low, TDLo ) indicates the lowest known toxic dose for a chemical compound or a mixture of substances, which causes a toxic or other adverse effects on the application in humans or animals. It is usually expressed in milligrams of the toxic substance per kilogram of body weight ( mg / kg) and depends crucially on the type of recording ( oral, inhalation, that is by the respiratory, dermal, by skin contact, intravenous, intramuscular, or intraperitoneal, d. h from the abdominal cavity).

Most data to TDLo values ​​are listed in the U.S. RTECS database.