Oxalobacter formigenes

Oxalobacter formigenes is an oxalate -degrading anaerobic bacterium that colonizes the large intestine of many vertebrates including humans occurs. O. formigenes lives in symbiosis with humans. Quinolone, a broad-spectrum antibiotic kills O. formigenes from the gastrointestinal tract. If this bacterium is missing in a subject lacking the primary source for the enzyme, oxalyl -CoA decarboxylase, which degrades calcium oxalate. If such a defect can promote the formation of kidney stones calciumoxalathaltigen.