Peter K. Vogt
Peter Klaus Vogt ( born March 10, 1932 in Broumov ) is a German-born American molecular biologist, virologist and geneticists. He is primarily concerned with retroviruses and viral and cellular oncogenes.
Life
Vogt studied, after he had fled in 1950 from the Soviet-occupied zone of Germany in the West, biology at the University of Würzburg. From 1955 on, he worked at the Max Planck Institute for Virology in Tübingen on his doctoral thesis and received his doctorate in 1959 at the University of Tübingen. Then he took (as Damon Runyon Cancer Research Fellow ) to a postdoctoral position in the laboratory of Harry Rubin at the University of California at Berkeley and began his work on the Rous sarcoma virus. In 1962 he moved to the University of Colorado at Denver, where he was first assistant and then associate professor. From 1967 to 1971 he was an associate professor and then as professor of microbiology at the University of Washington in Seattle before as Hastings professor transferred in 1971 to the University of Southern California, where in 1980 he became head of the Department of Microbiology. Since 1993 he is professor at the Scripps Research Institute in La Jolla.
Work
At the beginning of his scientific career Vogt specific interaction of the retroviral envelope proteins and their cellular receptors as the first condition for the infection. On the basis of this work it was possible for him to arrange the retroviruses of poultry in several strictly defined groups. This grouping allowed important cell biological work on retroviruses. In Seattle, he turned to the genetics of retroviruses. With his collaborator Kumao Toyoshima, he isolated the first temperature - sensitive mutants of a retrovirus and thus showed that virus- induced cancer is based on a function of the viral genome. In collaboration with the biochemist Peter Duesberg, he defined then the viral genome segment, which is necessary for tumor production, and thus discovered the first retroviral oncogene, src ( Src tyrosine kinase see ). His work on mutants of Rous sarcoma virus made it possible for Michael Bishop and Harold Varmus to demonstrate the cellular origin of all oncogenes. Through his extensive studies on poultry retroviruses Vogt also discovered other oncogenes, which currently play in human cancers an important role, such as Myc (along with Bister and Duesberg ), jun ( Maki and Bos ) and p3k ( with Chang).
Prices, honors and memberships
Vogt's work has been recognized by numerous awards and honors, including through the Irene - Vogeler Prize ( 1976), Alexander von Humboldt Award (1984 ), Ernst Jung Prize (1985 ), Robert J. and Claire Pasarow Prize (1987 ), Paul Ehrlich and Ludwig Darmstaedter Prize (1988 ), Bristol Myers award ( 1989), Charles S. Mott prize (1991) and the Albert Szent Györgyi prize ( 2010). 1995 Honorary Doctorate of the University of Würzburg, he was awarded. Vogt is a member of numerous national and international scientific societies, such as the National Academy of Sciences USA, the American Philosophical Society, the American Academy of Arts and Sciences, the German National Academy of scientists Leopoldina and the American Academy of Microbiology (AAM ) of the American Society for Microbiology (ASM). He is also in scientific committees and editorial boards operate, for example, at the Sidney Kimmel Foundation for Cancer Research (since 2005), the editorial board of the Proceedings of the National Academy of Arts and Sciences, USA (since 2000) and in editorial board for Current Topics in Microbiology and Immunology (Springer, 1967 ).
Private
Vogt is also committed painter. He took during his studies in Würzburg lessons with the landscape painter Josef Versl.