Policosanol

• Ateromixol
• CCRIS 7209

C10AX08

Almost white, odorless, crystalline powder

78-82 ° C

Insoluble in water, hexane, methanol and ethanol; slightly soluble in chloroform

> 5000 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search is not possible

Policosanol is a compound obtained from sugar cane or sugar cane wax mixture eight long-chain aliphatic alcohols. Partial Policosanol is also obtained from wheat germ or rice. Policosanol to lower blood lipid levels and is present in food supplements.

Composition

Main component of the policosanols is octacosanol, the further components differ in the chain length of the aliphatic alcohol.

Health-related use

Policosanol appears to inhibit cholesterol synthesis. An effect on blood lipid levels is controversial. Policosanol has a lowering total and LDL cholesterol and raising HDL cholesterol shown in some studies with mostly small number of subjects, which is to the extent resemble the effects of drugs from the statin family. Other studies did not go beyond the placebo effect intensity.

Also to inhibit the aggregation of platelets ( platelet aggregation) Policosanol.

Policosanol is not approved in European countries as a medicine. It is mainly promoted through the Internet, as a lipid-lowering dietary supplements and marketed.

Trade names

PPG, Lipo -Min