Ho studied at Queen's College in Hong Kong. He controls a group of eight casinos, including the Grand Lisboa Macau. In the 1960s, he also had nine casinos in the Philippines. These casinos he gave up when he came into conflict with the Philippine president. In addition to its casinos has Ho betting in football, horse racing and dog racing in China. For many years, the casino and entertainment industry in Macau was largely under the control of the Group STDM, the Ho belongs. This era ended in 2000, when the Chinese local government of Macau to the entertainment industry in Macau newly organized and aufteilte.
As a polygamist Ho is married to four wives and has 17 children. The singer and actress Josie Ho is a daughter from him.
In 2003, the Gold Bauhinia Star Ho of Hong Kong.
Also known as gourmet Stanley Ho and again creating headlines after he already paid 2007 330.000 U.S. dollars for a 1.5- pound truffle during an auction, he secured in 2008 for $ 200,000, a 1080 gram truffle.