Tricine

  • Tricine
  • N-( Tri (hydroxymethyl ) methyl ) glycine
  • N-[2 -hydroxy-1 ,1- bis (hydroxymethyl ) ethyl ] glycine
  • 2 - [ { 1,3- dihydroxy-2- (hydroxymethyl) propan-2- yl} amino ] acetic acid

Colorless crystals

Fixed

187 ° C.

  • PKS1: 2.3
  • PKa2: 8.15 (20 ° C)

0.8 mol / l in water at 0 ° C.

Template: Infobox chemical / molecular formula search available

N-( Tri (hydroxymethyl ) methyl ) glycine, and Tricine, is an organic chemical compound from the group of amino carboxylic acids and polyols.

Properties

Tricine is a zwitterion with pKS1 of 2.3 and a pKa2 of 8.6 (0 ° C) 8.15 (20 ° C) 8.05 (25 ° C) and 7.80 (37 ° C ). The temperature dependence of the acidity constant is -0.021 K -1 at ΔpKs2 =.

Tricine binds divalent metal ions with the following equilibrium constants ( pKM at 20 ° C): Mg2 1.2; Ca2 2.4; Mn2 2.7; Cu2 7.3.

Use

Tricine is used for biochemistry as a buffer substance, with a good buffer capacity between pH 7.4 to 8.8.

Tricine is used in TRIS - tricine SDS-PAGE gels.

CAS registry number PubChem Digital Object Identifier
589850
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