Weber's syndrome

The Weber syndrome (synonyms: hemiplegia alternans oculomotorica superior, hemiplegia alternans superior and Weber- Gubler 's palsy ) is a classic brain stem syndrome, which is caused by a localized tissue damage in the area of the midbrain foot, with parts of the substantia nigra destroyed and parts of the pyramidal tract, the tract corticopontinus and the root fibers of the oculomotor nerve to be interrupted. It is named after Hermann David Weber, a German -born doctor who practiced in London and described it in 1863.

Semiology

On the side of the lesion (ipsilateral ), there is a third nerve palsy, which leads to restrictions of eye movement and diplopia. The result is a Paralytic strabismus, and the pupil is wide and immobile. Due to the impairment of orbits that cross further caudally, it depends on the opposite side ( kontalateral ) to varying degrees, mostly spastic hemiplegia ( hemiparesis ) with rigid increased tone of the muscles and Dystaxie. Since the central ( supranuclear ) cars to the nuclei of the cranial nerves VII, IX. , X and XII. may also be affected, and central paresis of mimic facial, throat and tongue muscles on the contralateral side can be observed.

Causes

Cause of Weber 's syndrome is usually a brainstem infarction by occlusion of a branch ( ramus interpeduncularis ) of the posterior cerebral artery or the posterior choroidal artery. Conceivable, any other localized damage in this area, for example by an inflammatory oven.