Cytidine

  • C ( short code )
  • 1- β -D - Ribofuranosylcytosin
  • 1 - [( 2R, 3R, 4S, 5R ) -3,4- dihydroxy-5- (hydroxymethyl) oxolane -2-yl ] -4-amino -pyrimidin- 2-one

Fixed

210-220 ° C ( decomposition)

Soluble in water

2700 mg · m -3 ( LD50, mouse, ip)

Template: Infobox chemical / molecular formula search available

Cytidine is a nucleoside and consists of the nucleobase and the sugar cytosine β -D - ribose. The analogue with deoxyribose is the deoxycytidine.

Properties

Cytidine is a component of ribonucleic acid ( RNA), where it forms a base pair with guanosine.

Cytidine is an intermediate of the pyrimidine metabolism from the catalyzed by cytidine deaminase ( EC 3.5.4.5 ) deamination of uridine, cytidine 5' -monophosphate ( CMP), is formed by uridine - cytidine kinase ( EC 2.7.1.48 ) catalyzed phosphorylation. The latter is further phosphorylated via cytidine 5'- diphosphate ( CDP) to cytidine -5'-triphosphate (CTP). CDP or CTP serve inter alia as building blocks in the ribonucleic acid (RNA ) synthesis or as an activating group in the synthesis of lipids such as lecithin, cephalin and cardiolipin.

Degradation to cytosine is carried out by the catalytic activity of Pyrimidinnucleosidase ( EC 3.2.2.8 ).

Related compounds

Isomers

Methylated derivatives

Azaderivat

211209
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