Klaus Rajewsky
Klaus Rajewsky ( born November 12, 1936 in Frankfurt am Main ) is a German immunologist.
Scientific stations
He studied medicine in Frankfurt and Munich. Subsequently, he conducted research at the Pasteur Institute in Paris. From 1964 to 1970 Rajewsky was a research associate at the Institute for Genetics, University of Cologne. From 1970 he was professor of molecular genetics at the Institute of Genetics, University of Cologne until reaching retirement age in 2001. After his retirement in Germany and almost 40 years in Cologne, he joined the Harvard Medical School, at the Center for Blood Research in Boston. In 2011 he returned to Germany to conduct research at the Max Delbrück Center for Molecular Medicine ( MDC) Berlin-Buch.
In 1967 he was a founding member of the German Society of Immunology and from 1995 to 2001 Head of the European " Monterontondo Research Center " in Rome.
Research priorities
As one of the most influential scientists in his field Klaus Rajewsky has particularly contributed to the development of mutant mouse as animal models. In such mutant genes are specific to individual cell types taken out ( "knock-out ", "conditional knock-out", see knockout mouse ), or by genetic methods genes altered so that can be traced if they in a cell " " will be so implemented in functional proteins used ( " knock- in "). Rajewsky uses these models to analyze the development of B-lymphocytes. Another focus of his work is the leukemia research, particularly the further elucidation of the mechanisms of Hodgkin's lymphoma.
Family
His father is of German biophysicist and radiation researcher Boris Rajewsky (1893-1974) and his son is the German bioinformaticians Nikolaus Rajewsky (* 1968).