NLB stands for:
- National League B, the second highest league in most Swiss sports leagues
- Network Load Balancing, see Load Balancing ( computer science )
- Nova Ljubljanska banka, the largest bank in Slovenia
- NLB League, Adriatic basketball league, see Adriatic Basketball Association
- Northern Lighthouse Board ( NLB), the Scottish National Authority for Marine Navigation
- New Life Bible, a translation of the Bible
- Norsk lyd -og blindeskriftbibliotek which, Norwegian hearing and Braille Library '