In his native city and in Buenos Aires, he first studied medicine and music. Thanks to a grant from the Bariloche Foundation, he specialized in harpsichord, chamber music and performance practice. His career as a soloist and continuo player he began in Argentina with the renowned chamber orchestra Camerata Bariloche. Several he toured South America and Europe.
In his quest for authenticity, he built according to traditional models of the first harpsichords of his country. In 1978, Oscar Milani to Germany. A DAAD scholarship enabled him to continue his studies first in Lübeck and then in Geneva in Marinette Extermann.
At the Stuttgart College of Music, he studied with Kenneth Gilbert. There he completed his studies with the artistic audit as the best graduate of his class. This was followed by further courses at Johann Sonnleitner, Colin Tilney, Bob van Asperen, Gustav Leonhardt and others.
Oscar Milani is the initiator of numerous courses in Southern Germany, as the " Early Music Week" in Neuburg an der Donau. There, among other things, worked with Gabriel Garrido, Jean Tubéry, Paolo Pandolfo and Han Tol. Since 1981 he teaches at the College of Music Nuremberg and basso continuo harpsichord and since 1993 at the University for Protestant Church Music Bayreuth.
As a member of ensembles and as a soloist, he has played a lot of radio and CD recordings. The transcriptions of works by Astor Piazzolla and Bach's Orchestral Suites (jointly with Mario Raskin ) have the historical harpsichord made accessible to a wider audience.