Steven Rosenberg
Steven Aaron Rosenberg ( born August 2, 1940 in New York City ) is an American surgeon and cancer researcher at the National Cancer Institute. Rosenberg is considered a pioneer of cancer immunotherapy.
Life
Rosenberg was the child of Polish Jewish immigrants. He attended the prestigious Bronx High School of Science. Rosenberg graduated from the Johns Hopkins University in Baltimore, Maryland, in 1961 and 1964, a bachelor an MD as graduation from medical school. At the Peter Bent Brigham Hospital in Boston, Massachusetts, he served his time Medical Assistant ( internship and residency ) and acquired in 1968 with the work of Erythrocyte Membranes The protein on the adjacent Harvard University a Ph.D. in biophysics. He then stayed on as a research assistant to John David at Harvard University before he moved to the National Institutes of Health ( NIH) in Bethesda, Maryland. Since 1974 he has been head of the department of surgery. In 1979 he was appointed professor of surgery at the Uniformed Services University of the Health Sciences in Bethesda. In addition, he has been a professor of surgery at the George Washington University in Washington, DC since 1988.
Rosenberg is married to Alice O'Connell since 1968, the couple has three daughters.
Work
Rosenberg treated advanced malignancy with T- lymphocytes with interleukin -2 ( IL-2) to lymphokine killer cells ( LAK cells ) had been modified, and with tumor - infiltrating lymphocytes (tumor -infiltrating lymphocytes, TIL) with IL - 2 were stimulated. Together with W. French Anderson led Rosenberg, the first successful trials for gene therapy in humans by by einschleuste the gene for tumor necrosis factor ( TNF) in TIL. Rosenberg identified numerous tumor antigens, which are regarded as targets for the development of a " cancer vaccine ".
Rosenberg was speaker of the medical team that treated colon cancer in 1985 at the former U.S. president Ronald Reagan.