Denis Duboule

Denis Duboule ( born February 17, 1955 in Geneva ) is a Swiss- French developmental biologist and geneticist at the University of Geneva and the Ecole Polytechnique Fédérale de Lausanne.

Life

Duboule Studied at the University of Geneva biology and acquired there also a docteur en sciences ( Doctor of Science ). As a postdoctoral researcher or research group leader, he worked with Pierre Chambon at Strasbourg University and then at the European Molecular Biology Laboratory ( EMBL) in Heidelberg, before becoming a professor in 1992 went back to the University of Geneva. Since 1997, he heads up the Department of Zoology and Animal Biology. Since 2001 he leads the national research focus Frontiers in Genetics of the Swiss National Science Foundation.

Duboule is married and has four children.

Work

Duboule examined the colinearity, a principle by which the genes in vertebrates ( vertebrates ) control the development of the limbs, on the one hand along their temporal use during embryonic development, on the other hand along the body axis " front-back " of the type spatially arranged on the chromosomes are. He was able to show that the Hox genes play a crucial role in the development of the limbs. His discoveries have opened a new field of research, and contributed significantly to the understanding of the evolution of species.

Awards (selection)

227527
de