Hans Christian Hagedorn
Hans Christian Hagedorn ( born March 6, 1888 in Copenhagen, † October 6, 1971 in Gentofte ) was a Danish pharmacologist and diabetes researchers. He was co-developer of the Hagedorn -Jensen method for the measurement of blood glucose and the widespread under the name Neutral Protamine Hagedorn or NPH insulin first long-acting insulin product for the treatment of diabetes mellitus, and is considered one of the most outstanding Danish doctors in the first half of the 20th century.
Life
Hans Christian Hagedorn was born in 1888 in Copenhagen and graduated from the local university to study medicine. He then went to a small hospital in Herning in western Denmark, where he also met his wife there working as a dentist. After he had settled in the region as a general practitioner, he developed together with the local pharmacist Birger Norman Jensen a simple method for the determination of blood glucose, the roughly four decades was widely known, after its publication in 1918 because of their reliability and ease of implementation and under the name Hagedorn -Jensen method was known.
Shortly after the Spanish flu, he moved to a hospital in Copenhagen, where he received his doctorate in 1921 on the regulation of blood sugar levels. In defending his doctoral thesis, he met August Krogh know, who in 1920 received the Nobel Prize in Physiology or Medicine, and his wife was suffering from diabetes mellitus. During a lecture tour of Canada in 1922 Krogh learned of the results of the first clinical applications of the hormone insulin, which had previously discovered Frederick Banting and Charles Best, a short time, and received the approval for the production of insulin in Denmark. Hagedorn founded for this purpose, the Nordisk Insulin Laboratory and later developed from protamine and porcine insulin, the first long-acting insulin preparation that is still one of Neutral Protamine Hagedorn under the name or NPH insulin to the most commonly used insulins. 1932 was beyond the Steno Memorial Hospital in Copenhagen, which functioned as a research hospital of the Nordisk Insulin Laboratory and the Hagedorn led for 26 years as a senior consultant. As the meantime occurred bottlenecks in the availability of pancreatic from slaughter animals for insulin production, he examined the suitability of up to 50 kilograms pancreata of whales. He thereby led to the isolation of Wal- insulin on board a whaling ship, but the process proved to be too expensive for practical use.
During the Second World War, he refused any cooperation with the German occupying forces. A request asked of him by the German Red Cross, which he regarded as a prerequisite for delivery of insulin after Germany took place, at any time. Hagedorn himself later fell ill from diabetes and died in 1971 in Gentofte to the consequences of a long-standing Parkinson's disease.
Awards and appreciation
Hans Christian Hagedorn received in 1938 by the University of Oslo and the University of Gothenburg in 1954 by an honorary doctorate. He died shortly before in a ceremony planned to mark the 50th anniversary of the discovery of insulin receiving an honorary doctorate by the University of Toronto. The European Association for the Study of Diabetes (EASD ) in 1965 appointed him an honorary member. Named after him include the Hagedorn Research Center in Gentofte, an endowment founded by Novo Nordisk and in 2002 conferred by the German Diabetes Society Research Promotion price and outstanding since 2009 and also sponsored by Novo Nordisk Foundation professorship at the Technical University of Dresden.