1921–22 Maltese Premier League
The First Division 1921/22, was the eleventh season in the history of the highest Maltese Football League. Champion for the fifth time the FC Floriana.
Clubs
In comparison to the previous season Marsa United, United Paola, Qormi United and Msida Rangers waived participation.
Mode
The season was played in a single round. For a victory, there were two points, one for a draw and a defeat for no point. Case of a tie a play for the championship was held.