In 2001, she won the title at the U.S. Championships in the 100 -meter run. International she appeared, among others, as the winner of the 1995 Pan American Games in Mar del Plata in the 100 meters and third parties as at the IAAF World Indoor Championships in Lisbon in 2001 over 60 meters in appearance.
However, their greatest achievements came as a member of the U.S. 4 × 100 m relay. She won the relay gold medal at the 1996 Olympics in Atlanta and two gold medals and one silver medal at World Championships in Athletics.
At the Olympic Games in Sydney in 2000, she took together with Marion Jones, Torri Edwards and Nanceen Perry in third place. 2007 Marion Jones confessed, however, the abuse of drugs and gave her five Olympic medals from Sydney back, including the bronze medal in the 4 × 100 m relay. The following year, the Executive Committee of the International Olympic Committee decided also their teammates withdraw the medal.
Gaines himself was in the BALCO affair retroactive to June of the year closed in December 2005 because of the use of banned substances by the USADA for two years, as well as all results were canceled in November 2003. After the expiry of lock they failed to qualify for the 2008 Olympic Games in Beijing clearly.
Chryste Gaines is 1,70 m tall and had a competition weight of 57 kg.