Janet Rossant

Janet Rossant ( born July 13, 1950 in Chatham, United Kingdom) is a British- Canadian developmental biologist and geneticist.

Life

Rossant acquired in 1972 from the University of Oxford, England, a master's degree in zoology and 1976 at Richard L. Gardner at the University of Cambridge a Ph.D. with a dissertation on the developmental biology of mammals. As a postdoctoral fellow, she worked again at the University of Oxford before 1977 first professorship ( Assistant Professor ) of biology at Brock University in St. Catharines, Canada, was presented. In 1981, she became associate professor there. In the same year she received an additional job as an adjunct professor of pathology at McMaster University in Hamilton. In 1985 Rossant as associate professor of medical genetics at the University of Toronto, 1988, she was awarded a full professorship there. From 1985 to 2002, she conducted research at the Samuel Lunenfeld Research Institute in addition at Mount Sinai Hospital in Toronto. In addition, Rossant (as of 2013) Director of Research in the Department of Developmental Biology and Stem Cell Research at the Hospital for Sick Children in Toronto, has been a professor of Molecular Genetics at the University of Toronto and head of the Centre for Modeling Human Disease, also in Toronto.

Work

Rossant could significantly contribute with their work on the mouse model organism for understanding the entire reproductive and developmental cycle of mammals. She developed numerous techniques to track the fate of individual cells or the change of individual genes. Rossant created several mouse models, the basis of which can be studied human congenital malformations and other disorders. With her work she tries to understand the genetic basis of the development of early cell lines and the development of stem cells. Particular attention it focused on the formation of the blastocyst and trophoblast, the development of the earliest orientation in the embryo and the signaling pathways that control the development of the vascular system.

Awards (selection)

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