Cassano Spinola ( Piedmontese Cassan, in the local dialect Cassau ) is a municipality with 1763 (as of 31 December 2012) a population of Alessandria in the Italian province (AL ), Region Piedmont.
The village lies at an altitude of 191 m above sea level. The municipality covers an area of 14.97 km ². Through the municipal area of the river Scrivia flows.
The neighboring municipalities are Carezzano, Gavazzana, Novi Ligure, Pozzolo Formigaro, Sant'Agata Fossili, Sardigliano, Serravalle Scrivia, Stazzano and Villalvernia.
- The cyclist Andrea Carrea (1924-2013) lived all his life in Cassano Spinola.