Together with his twin brother Mike Bryan, it forms one of the most successful tennis doubles, the present and is currently at the top of the ATP Double world rankings.
Among his greatest successes include fifteen Grand Slam titles in doubles competition together with his brother Mike and seven Grand Slam titles in mixed competition with different partners. His first Grand Slam he won with Mike in 2003 at the French Open 2003. Following titles they won in succession at the 2005 U.S. Open, the Australian Open in 2006 and Wimbledon in 2006. Thus Bob and Mike Bryan completed already with the fourth title win their career Grand Slam. There were other titles at the Australian Open and the U.S. Open, and two more in Wimbledon. However, your success at the French Open in 2003 they were able to repeat in 2013. With their victories at the U.S. Open in 2012, and at the other three Grand Slams in the following season, 2013, Bob and Mike Bryan completed a fake Grand Slam. 2003, 2004 and 2009, she also won the ATP World Tour Finals and the Tennis Masters Cup. With currently 325 weeks at the top of the double world rankings (all together with his brother Mike) lies behind his brother Bob Bryan (341) ranked two of the players with the most leadership weeks in the rankings.
Bob Bryan joined 2004, 2008 and 2012 at the Olympic Games for the United States. In Athens in 2004 he was put together with Mike at one position without dropping a set and reached the quarter-finals. There, they lost against the later gold medalists Fernando González and Nicolás Massú from Chile in straight sets. At the 2008 Games in Beijing, he won with Mike after a victory over the French Arnaud Clément and Michaël Llodra the bronze medal in doubles. In the semifinals, the brothers were subject to the future Olympic champions Roger Federer and Stanislas Wawrinka of Switzerland. In 2012, Bob Bryan joined not only the men's doubles with his twin brother, but this time also in the mixed doubles. However, together with Liezel Huber he failed already in the opening round to Sabine Lisicki and Christopher Kas. Bob and Mike Bryan, however, were able to win the doubles competition for the first time: in two sets in the final they defeated Michaël Llodra and Jo -Wilfried Tsonga and thus won the gold medal. By winning the Olympic gold medal he and Mike completed, also their career Gold Slam, which also requires winning all four Grand Slam titles in addition to the gold medal.
Since 2003, Bob Bryan plays for the U.S. Davis Cup team. He and his brother Mike are common with 20 victories, the most successful double of Americans in Davis Cup history. He was on the team that won the Davis Cup in 2007.
Bob Bryan married in December 2010, the Attorney Michelle Alvarez. The couple has a daughter (* 2012) and a son (* 2013).