San Cesareo is a municipality in the province of Rome in the Italian region Latium, located about 14,161 inhabitants (as of 31 December 2012). It is located 39 km east of Rome.
The community was until 1990 a part of the community Zagarolo.
San Cesareo lies in the valley of the Sacco, between the Alban Hills and the Prenestini. It is a member of the Comunità Montana dei Castelli Romani e Prenestini.
Pietro Panzironi was elected in April 2008 to the mayor.